Published Data

• Summary of Presented Data for Paroxysmal and Persistent Atrial Fibrillation (PDF Download)

Manuscripts & Commentary

	Sipötz J, Gwechenberger M, Richter B, Adlbrecht C, Kornfeld G, Gössinger HD. Treatment of a Recurrent Atrial Tachycardia by Isolation of the Right Inferior Pulmonary Vein using a Multi-Electrode Duty Cycled Ablation Catheter. Europace. Epub ahead of print 21 Jul 2010.
	Lau M, Hu B, Werneth R, Sherman M, Oral H, Morady F, Krysl P. A Theoretical and Experimental Analysis of Radiofrequency Ablation with a Multielectrode, Phased, Duty-Cycled System. PACE. Epub ahead of print 10 Jun 2010.
	BULAVA A, HANIŠ J, SITEK D, OŠMERA O, KARPIANUS D, ŠNOREK M, ŘEHOUŠKOVÁ K, TOUŠEK F, and PEŠL L. Catheter Ablation for Paroxysmal Atrial Fibrillation: A Randomized Comparison between Multielectrode Catheter and Point-by-Point Ablation. PACE. Epub ahead of print 28 May 2010.
	Deneke T, Shin DI. Novel Technique for Atrial Fibrillation Ablation: Use of Anatomically Designed Pulmonary Vein Ablation Catheter. Hospital Chronicles 2010, 5(2): 95–98.
	McWilliams E, Giles J, Furniss S. Pulmonary Vein Stenosis may still Occur after Ablation. Europace Epub ahead of print April 25, 2010.
	Raffa S, Große A, Brunelli M, Wauters K, Geller JC. Voltage Mapping and Pacing to Assess the Level of Pulmonary Venous Isolation Achieved with a Novel Circular Multielectrode Ablation Catheter. Europace. Epub 21 April 2010, 10.
	De Greef Y, Schwagten B, De Keulenaer G, Stockman D. Pulmonary Vein Stenosis after PVAC-Guided PV Isolation. Heart Rhythm. 2010 Apr 12.
	Shah, D. Editorial in Response to Beukema Study: Pulmonary Vein Isolation with the Pulmonary Vein Ablation Catheter (PVAC): Is There a Price to Pay for a ‘Simpler’, Shorter Procedure? Europace (2010) 12(4): 455-457.
	Spitzer S, Karolyi L. Catheter Ablation of Atrial Fibrillation with a Novel, Duty-Cycled Ablation System. Clin Res Cardiol Suppl (2010) 5:51–56.
	Almeida S, Cavaco D, Adragao P, et al. Atrial Fibrillation Ablation using Simultaneous Multielectrode Application of Radiofrequency Energy. Rev Port Cardiol 2010; 29 (01): 125-137.
	Miyazaki S, Wright M, Haïssaguerre M, Hocini M. Ablation of Long-standing Persistent Atrial Fibrillation with Multielectrode Ablation Catheter. Heart Rhythm. Epub 2010 Mar 3.
	Reddy V. Beyond PV Isolation for Ablation of Persistent AF. Nature Reviews Cardiology 7, 121-122 (March 2010).
	Beukema R, Beukema W, Smit JJJ, et al. Efficacy of Multi-Electrode Duty-Cycled Radiofrequency Ablation for Pulmonary Vein Disconnection in Patients with Paroxysmal and Persistent Atrial Fibrillation. Europace (2010) 12(4): 502-507.
	Katritsis DG, Giazitzoglou E, Paxinos G. Use of a Circular Mapping and Ablation Catheter for Ablation of Atypical Right Ventricular Outflow Tract Arrhythmia. Europace (2010) 12(2): 277-278.
	Hayes CR, Keane D. Safety of Atrial Fibrillation Ablation with Novel Multi-Electrode Array Catheters on Uninterrupted Anticoagulation—A Single-Center Experience. J Interv Card Electrophysiol. 2010 Mar;27(2): 117-122.
	Wieczorek M, Hoeltgen R, Brueck M, Bandorski D, Akin E, Salili AR. Pulmonary Vein Isolation by Duty-Cycled Bipolar and Unipolar Antrum Ablation using a Novel Multielectrode Ablation Catheter System: First Clinical Results. J Interv Card Electrophysiol. 2010 Jan; 27(1):23-31.
	Duytschaever M, Anne W, Papiashvili G, Vandekerckhove Y, Tavernier R. Mapping and Isolation of the Pulmonary Veins Using the PVAC Catheter. PACE 2009; 33(2): 168-178.
	Deneke T, de Groot JR, Horlitz M, Mügge A, Grewe PH, Bünz K, Bastian A, Haberkorn-Butendeich R and Shin DI. Pulmonary Vein Isolation using a Novel Decapolar Over-the-Wire Mapping and Ablation Catheter. Expert Rev Cardiovasc Ther. 2009 Nov;7(11):1341-7.
	Wieczorek M, Hoeltgen R, Akin E, Salili AR, Oral H, Morady F. Results of Short-Term and Long-Term Pulmonary Vein Isolation for Paroxysmal Atrial Fibrillation Using Duty-Cycled Bipolar and Unipolar Radiofrequency Energy.  J Cardiovasc Electrophysiol. Vol 21 (4) 399 - 405.
	Scharf C, Boersma L, Davies W, Kanagaratnam P, Peters N, Paul V, Rowland E, Grace A, Fynn S, Dang L, Oral H, Morady F.  Ablation of Persistent Atrial Fibrillation Using Multi-Electrode Catheters and Duty-Cycled Radiofrequency Energy.  J Am Coll Cardiol, 2009; 54:1450-1456
	Sabine Fredersdorf, Stefan Weber, Clemens Jilek, Norbert Heinicke, Christian Von Bary, Carsten Jungbauer, Gnterüter A. Riegger, Okka W. Hamer, Andreas Jeron, Safe and Rapid Isolation of Pulmonary Veins Using a Novel Circular Ablation Catheter and Duty-Cycled RF Generator. J Cardiovasc Electrophysiol, Vol. 20, pp. 1097-1101, October 2009
	Maurits C.E.F. Wijffels, Matthijs Van Oosterhout, Lucas V.A. Boersma, Randy Werneth, Chris Kunis, Betty Hu, Jet D.M. Beekman, Marc A. Vos, Characterization of In Vitro and In Vivo Lesions Made by a Novel Multichannel Ablation Generator and a Circumlinear Decapolar Ablation Catheter. J Cardiovasc Electrophysiol, Vol. 20, pp. 1142-1148, October 2009
	Boersma L, Mulder A, Jansen W, Wever E, Wijffels M.  Voltage Analysis after Multi-Electrode Ablation with Duty-Cycled Bipolar and Unipolar Radiofrequency Energy: A Case Report. Europace. 2009 Nov;11(11):1546-8.
	Ho J, Nakahara S, Shivkumar K, Mahajan A.  Live Three-Dimensional Transesophageal Echocardiographic Imaging of Novel Multi-Electrode Ablation Catheters.  Heart Rhythm Journal. Published online July 21, 2009
	Bauerle H, Japha T, Gonska BD.  Pulmonary Vein Isolation with Multipolar Ablation Catheters for the Treatment of Paroxysmal Atrial Fibrillation.  Schwerpunkt Herzschr Elektrophys 2009; 20:82–89
	Boersma, L.V.A., Wijffels, M.C.E.F., Oral, H., Wever, E.F.D.,Morady, F., Pulmonary Vein Isolation by Duty-Cycled Bipolar and Unipolar RF Energy with a Multi-Electrode Ablation Catheter. Heart Rhythm 2008; 5:1635-1642.
	Kistler, P.M., Multi-Eelectrode Ablation for Paroxysmal Atrial Fibrillation: Pulmonary Vein Isolation Made Easy?, Heart Rhythm 2008; 5: 1643-1644.

Abstracts

1. Yuan S, Kongstad O. Duty-cycled Unipolar-Bipolar RF Ablation via Multi-electrode in Patients with Paroxysmal Atrial Fibrillation. Eur Heart J 2009 30: 270 [Abstract # P1621]
   
   
2. Elvan A, Beukema W, Smit J, Delnoy P, Ramdat Misier A. Validation of PVI of Multi-electrode Duty Cycled Radiofrequency Ablation in Patients with Paroxysmal and Persistent Atrial Fibrillation. Eur Heart J 2009 30: 273 [Abstract # P1635]
   
   
3. Tuan J, Jeilan M, Kundu S, Osman F, Stafford P, Ng G. Comparison of a New Circular Ablation Catheter with Conventional Approach for Pulmonary Vein Isolation. Eur Heart J 2009 30: 813 [Abstract # P4824]
   
   
4. Brunelli M, Raffa S, Grosse A, Wauters K, Geller J. Acute Efficacy and Safety of a Novel Circular Multielectrode Radiofrequency Ablation Catheter for Pulmonary Vein Isolation in Paroxysmal Atrial Fibrillation. Eur Heart J 2009 30: 814 [Abstract # P4825]
   
   
5. Abdelaal A, Magnin-Poull I, Andronache M, Cedano J, Groben L, Magalhaes S, Muresan L, Boudoucha N, Aliot E, De Chillou C. On Wire Technology for Pulmonary Veins Isolation: Comparison between Phased Array Radiofrequency Ablation and Balloon-Cryotherapy. Eur Heart J 2009 30: 909 [Abstract # P5213]
   
   
6. Brunelli M, Raffa S, Grosse A, Regoli F, and Geller JC.  Acute Efficacy of a Novel Circular Multielectrode Ablation Catheter for Pulmonary Vein Isolation: an Anatomic Analysis Using 3‐D CT Reconstruction of the Left Atrium.  Europace 2009; 11 (S6), Abstract 93
   
   
7. Wieczorek M, Hoeltgen R, Braun P.  Duty-Cycled Bipolar/Unipolar Antrum Ablation in Drug-Refractory Paroxysmal Atrial Fibrillation using a Novel Multielectrode Ablation Catheter System.  Europace 2009; 11(S6), Abstract 292.
   
   
8. Mulder A, Wijffels M, Wever E, and Boersma LVA.  Longterm Results of Multi‐Electrode Pulmonary Vein Isolation with Bipolar/Unipolar RF Energy for Paroxysmal AF.  Europace 2009; 11 (S6), Abstract 385.
   
   
9. Elvan A, Smit JJ, Beukema W, Delnoy PP, and Misier AR.  Validation of PV Isolation Using Multi-electrode Duty Cycled Radiofrequency Ablation in Patients with Paroxysmal and Persistent Atrial Fibrillation.  Europace 2009; 11(S6), Abstract 406.
   
   
10. Tuan J, Chung I, Jeilan M, Kundu S, Osman F, Stafford P, Ng GA.  Pulmonary Vein Isolation for Paroxysmal Atrial Fibrillation: Comparison of a New Circular Ablation Catheter with Conventional Approach.  Europace 2009; 11(S6), Abstract 407.
    
    
11. Mulder A, Wijffels M, Wever E, and Boersma LVA.  Multi‐Electrode Pulmonary Vein Isolation and Left Atrial CFAE Ablation for Chronic AF with Bipolar and Unipolar RF Energy: Longterm Results and Follow‐Up.  Europace 2009; 11 (S6), Abstract 664.
    
    
12. Raffa S, Grosse A, Brunelli M, Regoli F, and Geller JC.  Novel Circular Multielectrode Ablation Catheter for Atrial Fibrillation Ablation: Assessment of the Level of Pulmonary Venous Isolation by Voltage Mapping.  Europace 2009; 11 (S6), Abstract 991.
    
    
13. Raffa S, Grosse A, Brunelli M, Regoli F, and Geller JC.  Novel Circular Multielectrode Ablation Catheter for Atrial Fibrillation Ablation: Assessment of the Level of Pulmonary Venous Isolation by Voltage Mapping.  Heart Rhythm 2009; 6 (Suppl):S110. [PO01-42]
    
    
14. Elvan A, Smit JJ, Beukema W, Delnoy PP, and Misier AR.  Validation of PV Isolation Using Multi-electrode Duty Cycled Radiofrequency Ablation in Patients with Paroxysmal and Persistent Atrial Fibrillation.  Heart Rhythm 2009; 6 (Suppl):S53. [AB25-1]
    
    
15. Yuan S, and Kongstad O.  Duty-cycled, Unipolar-bipolar RF Ablation via Multi-electrode Catheter in Patients with Paroxysmal Atrial Fibrillation.  Heart Rhythm 2009; 6 (Suppl):S279. [PO04-37]
    
    
16. Brunelli M, Raffa S, Grosse A, Regoli F, and Geller JC.  Efficacy of a Novel Circular Multielectrode Ablation Catheter for Pulmonary Vein Isolation: an Anatomic Analysis Using 3‐D CT Reconstruction of the Left Atrium.  Heart Rhythm 2009; 6 (Suppl):S404. [PO06-38]
    
    
17. Brunelli M, Raffa S, Grosse A, Regoli F, and Geller JC.  Acute Efficacy and Safety of a Novel Circular Multielectrode Radiofrequency Ablation Catheter for Pulmonary Vein Isolation in Paroxysmal Atrial Fibrillation.  Heart Rhythm 2009; 6 (Suppl):S405. [PO06-40]
    
    
18. Mulder A, Wijffels M, Wever E, and Boersma LVA.  Multi‐Electrode Pulmonary Vein Isolation and Left Atrial CFAE Ablation for Chronic AF with Bipolar and Unipolar RF Energy: Longterm Results and Follow‐Up.  Heart Rhythm 2009; 6 (Suppl):S215. [PO03-36]
    
    
19. Mulder A, Wijffels M, Wever E, and Boersma LVA.  Longterm Results of Multi‐Electrode Pulmonary Vein Isolation with Bipolar/Unipolar RF Energy for Paroxysmal AF.  Heart Rhythm 2009; 6 (Suppl):S277. [PO04-33]
    
    
20. Wieczorek M, Hoeltgen R, Braun P.  Pulmonary Vein Isolation by Antral Ablation using a Novel Duty-Cycled Bipolar/Unipolar Radiofrequency Energy Generator with a Multielectrodes Ablation Catheter.  J Interv Card Electr 2009; 24:225. [Abstract11-5]
    
    
21. Wieczorek M, Höltgen R, Braun P, Lawrenz M. Therapie des paroxysmalen Vorhofflimmerns mittels antraler Ablation durch ein Leistungs-moduliertes neuartiges Ablationssystem. Clin Res Cardiol 2009; 98, Suppl 1 (V82).
    
    
22. Erdogan A, Vogelsang P, Franzen W, Greiß H, Most A, Neuhof C, Soydan N, Gündüz D, Stracke S, Parahuleva M, Tillmanns H. Radiofrequenz-Katheterablation von Vorhofflattern zwischen gepulster versus konventioneller Technologie mit 8mm-tip bzw. multipolaren Ablationskathetern. Clin Res Cardiol 2009; 98, Suppl 1 (V98).
    
    
23. Brunelli M, Raffa S, Grosse A, Regoli F, and Geller JC. Acute Efficacy and Safety of a Novel Circular
    Multielectrode Radiofrequency Ablation Catheter for Pulmonary Vein Isolation in Paroxysmal Atrial Fibrillation. DKG 2009; Abstract 1891.
    
    
24. Brunelli M, Raffa S, Grosse A, Regoli F, and Geller JC. Acute Efficacy of a Novel Circular Multielectrode Radiofrequency Ablation Catheter for Pulmonary Vein Isolation: an Anatomic Analysis Using 3-D CT Reconstruction of the Left Atrium. DKG 2009; Abstract 1883.

1. Weber S, Fredersdorf S, Jilek C, Heinicke N, Jungbauer C, Husser O, Jeron A. Isolation Of Pulmonary Veins Using A Novel Decapolar Catheter For Mapping And Ablation. Circ 2008. 118: S_925-b [Abstract 4653].
   
   
2. Murray S, Adam Z, Horne A, Humphries V, Mahjid S. Adoption of a multi-electrode, phased radiofrequency ablation system for atrial fibrillation ablation by a single operator: outcomes and comparison to 3D mapping system guided, double trans-septal technique. Europace 2008; 10 (Supp 2): ii5.
   
   
3. James SA, Shepherd EJ, Gall SA, Neville-Smith KE, Furniss SS, Lord SW, Bourke JP. The impact of novel multi-array catheters on procedure time and outcome for ablation of atrial fibrillation. Europace 2008; 10 (Supp 2): ii23.
   
   
4. Boersma LVA, Scharf C, Davies W, Kanagaratnam P, Paul V, Rowland E, Grace A, Fynn S, Oral H, Morady F. Multi-electrode ablation with duty-cycled low power bipolar/uniplolar RF energy for chronic AF. Eur Heart J 2008;29:410  [Abstract: P2621]
   
   
5. Boersma LVA, Wijffels MCE, Wever EFD, Oral H, Morady F. PV antrum ablation for PAF by duty-cycled bipolar/unipolar RF energy through a novel circular decapolar catheter. Eur Heart J 2008;29:409  [Abstract: P2619]
   
   
6. Wijffels MCEF, Van Oosterhout MF, Vos MA, Beekman JD, Boersma LVA. Characterization of lesions in swine atrium using novel multi-electrode ablation catheters. Eur Heart J 2008;29 (Abstract Suppl):412 [Abstract #: P2632]
   
   
7. Fredersdorf S, Weber S, Jilek C, Jungbauer C, Schneider HJ, Jeron A. Safe And Fast Isolation Of Pulmonary Veins Using A Novel Circular Ablation Catheter. Europace 2008; 10 (Supp 1): i184.
   
   
8. Dang L, Boersma L, Oral H, Morady F, Candinas R, Scharf C. Multi-Electrode Catheters Using Low Energy Phased Radiofrequency For Ablation Of Chronic Atrial Fibrillation. Europace 2008; 10 (Supp 1): i184.
   
   
9. Dang L, Oral H, Morady F, Candinas R, Scharf C. Low energy phased radiofrequency for multielectrode ablation of paroxysmal atrial fibrillation (abstract). Heart Rhythm 2008; 5 (Suppl):S18. [AB9-3]
   
   
10. Boersma LVA, Wijffels MC, Wever EFD, Oral H, Morady F. Clinical efficacy of PV antrum ablation for AF by duty-cycled RF energy thorough a novel circumlinear decapolar catheter (abstract). Heart Rhythm 2008; 5 (Suppl):S19. [AB9-5]
    
    
11. Michaud GF, Martin DT, John RM, Daubert JP, Knight BP, Hummel JD, Kalbfleisch SJ, Weiss R, Hoyt R, Bailin S, Swarup V, Bahu MM.  Safety using novel multi-array catheters and phased radiofrequency energy in left atrial ablation for persisent atrial fibrillation (abstract). Heart Rhythm 2008; 5 (Suppl):S313-314. [PO5-17]
    
    
12. Boersma LVA, Wijffels MC, Wever EFD, Oral H, Morady F. Acute Results of PV antrum albation by a novel circumlinear decapolar catheter with low power duty-cycled RF energy (abstract). Heart Rhythm 2008; 5 (Suppl):S368-369. [PO6-32]
    
    
13. Scharf C, Boersma LVA, Kanagaratnam P, Davies DW, Peters NS, Paul V, Rowland E, Fynn SP, Grace AA. Long Term Efficacy When Using Multi-Array Catheters and Phased Radiofrequency Energy for Ablation of Chronic Atrial Fibrillation (abstract). J Am Coll Cardiol. 2008;51(10):A8. [1008-94]

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